Alprazolamum

Alprazolam; 8-chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine · Xanax, Xanax XR, Niravam (brand names); a triazolobenzodiazepine

Modern MM

Modern drug remedy whose sphere of action, by analogy to its toxicology, centers on the central nervous system: sedation, mental dullness, impaired memory and coordination, and the rebound/withdrawal states of anxiety, insomnia and agitation. No formal proving symptomatology exists.

Key symptoms

No formal homeopathic proving of Alprazolam has been published, so there are no verified keynotes or characteristic indications. Any clinical use rests on analogy to the drug's documented pharmacological/toxic picture: profound sedation and drowsiness; mental dullness with impaired memory and decreased alertness; ataxia, poor coordination and slurred speech; and the withdrawal/rebound state of anxiety, insomnia, tachycardia and restlessness. Paradoxical irritability, aggression and hypomania are also on record. These are toxicological observations, NOT proving symptoms.

Worse (aggravation)

Not established. No proving-derived modalities exist for this remedy.

Better (amelioration)

Not established. No proving-derived modalities exist for this remedy.

Manohar V Nagaiah

Materia Medica of Modern Homeopathic Medicine · 2026

Xanax, Xanax XR, Niravam (brand names); a triazolobenzodiazepine

Source & Nature

Alprazolamum is the homeopathic preparation of alprazolam, a synthetic triazolobenzodiazepine anxiolytic (molecular formula C17H13ClN4, CAS 28981-97-7, PubChem CID 2118). The drug was developed by Jackson B. Hester Jr. at the Upjohn Company, patented in 1971 and FDA-approved in 1981. It is best known under the brand name Xanax and is among the most widely prescribed psychiatric medications worldwide, used for generalized anxiety disorder, panic disorder and anxiety with depression.

Preparation

The remedy is prepared from the alprazolam drug substance by standard homeopathic methods: centesimal trituration with lactose/saccharose for the lower steps (typically through C6), then serial liquid potentization in ethanol-water. The homeopathic pharmacy Remedia (Eisenstadt, Austria) lists Alprazolam as saccharose globules in C potencies from C3 to C200, as ethanol-water dilutions (C30-C200), and as Korsakovian potencies (1MK, 10MK), made on demand.

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Classical texts are in the public domain. Educational reference only — not medical advice.