Amphetaminum sulfuricum

Amphetaminum sulphuricum; Amphetamine sulfate; bis(1-phenylpropan-2-amine) sulfate / (RS)-1-phenylpropan-2-amine sulfate (2:1); CAS 60-13-9; PubChem CID 6055; molecular formula C18H28N2O4S · Amphetamine sulphate, racemic (dl-) amphetamine sulfate, "speed" (illicit street form), Benzedrine (historical brand of the sulfate salt)

Modern MM

A modern, sparsely documented remedy whose sphere of action is inferred from amphetamine toxicology: the central nervous system and sympathetic system — a state of excessive stimulation, sleeplessness, restlessness, racing mind, and, at the extreme, paranoid/agitated psychosis with collapse following over-excitation.

Key symptoms

There are NO proving-derived keynotes for this remedy. By analogy with the well-documented toxicology of amphetamine sulfate (Law of Similars), the corresponding state would be: intense restlessness and inability to keep still; insomnia with a racing, overactive mind; loss of appetite; tremor; rapid pulse and palpitation; dilated pupils; flushing and overheating; talkativeness and excitement progressing to anxiety, irritability and aggression; and, in extreme states, paranoid delusions and hallucinations resembling schizophrenia, followed by exhaustion and collapse. These are toxicological correspondences (StatPearls; FDA/DailyMed), not verified homeopathic symptoms.

Worse (aggravation)

Not established by proving. No reliable modalities are recorded in the homeopathic literature for this remedy.

Better (amelioration)

Not established by proving. No reliable modalities are recorded in the homeopathic literature for this remedy.

Manohar V Nagaiah

Materia Medica of Modern Homeopathic Medicine · 2026

Amphetamine sulphate, racemic (dl-) amphetamine sulfate, "speed" (illicit street form), Benzedrine (historical brand of the sulfate salt)

Source & Nature

Amphetaminum sulfuricum is the homeopathic potentization of amphetamine sulfate, the sulfuric-acid salt of racemic (RS)-amphetamine. It is a synthetic central-nervous-system stimulant of the substituted-phenethylamine class (molecular formula C18H28N2O4S; CAS 60-13-9; PubChem CID 6055), in which two molecules of amphetamine base are combined with one sulfate anion. Pharmacologically the parent drug acts mainly on the norepinephrine and dopamine systems as a releasing agent and reuptake inhibitor, producing arousal, wakefulness, appetite suppression and euphoria. It was historically sold as Benzedrine and remains a controlled prescription medicine (ADHD, narcolepsy) as well as a common illicit stimulant.

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