Hydrastinum muriaticum
Hydrastine hydrochloride · Plant · Ranunculaceae
Hydrastinum muriaticum is the first isolated alkaloid of Hydrastis, used primarily for local application to ulcerated mucous membranes including aphthous sore mouth, malignant or simple ulcers, and ozaena. Old school practitioners also used it internally for uterine haemorrhage. The alkaloids of Hydrastis as a group deserve separate proving.
Key symptoms
- Aphthous ulcers of the mouth
- Malignant or simple ulcers (local application)
- Ozaena (nasal ulceration with offensive discharge)
- Uterine haemorrhage

Muriate of Hydrastia. C21 H21 NO6 NCl.
Clinical
Cancer. Mouth, ulcer of, Ozæna. Ulcer.
Characteristics
This is the first alkaloid of Hydrastis that was isolated. Hale commends it as excellent for local applications, in the strength of about ten grains to eight ounces, stronger or weaker according to sensitiveness, in cases of aphthous sore mouth, ulcers (malignant or simple), ozæna, and generally in cases for which Hydrastis is being given internally. The alkaloids of Hydrastis deserve separate proving. Old school practitioners have used this salt largely as an internal remedy in uterine hæmorrhage.
Classical texts are in the public domain. Educational reference only — not medical advice.