Macrotinum
Actaea racemosa (Cimicifuga) resinoid · Plant · Ranunculaceae
Macrotinum suits women with melancholic, irritable states combined with muscular weakness and restlessness that paradoxically improves with movement. It is particularly indicated in menstrual disorders where neuralgic and muscular symptoms are worst before menstruation and dramatically improve once the flow is established.
Key symptoms
- Melancholy and irritability better when menses come on
- Intense pain at occiput worse at every throb of heart with retraction of head and neck
- Dull headache beginning in occiput extending to vertex and forehead
- Eyes and breasts worse before menses; better as soon as flow starts
- Dark circles around eyes week before menses disappearing when menses come on
- Pain in whole back as if muscles bruised; better by pressure and after menstruation
- Muscular exhaustion after least exertion; great restlessness
- Faint feeling in epigastrium extending over chest and head with throbbing over whole body
Worse (aggravation)
- Before menses (eyes, breasts, mental symptoms)
- During menses (bearing down, tight sensation around hips)
Better (amelioration)
- Onset of menses (most symptoms except dysmenorrhoea)
- After menstruation (backache)
- Moving about (despite weakness)
- Pressure (headache, back pain)
- Sleep (headache temporarily)

Macrotyn. Resinoid of Actæa racemosa. Trituration.
Clinical
Dysmenorrhœa. Eyes, affections of. Headache. Lumbago. Melancholy. Myalgia. Rheumatism.
Characteristics
I have already mentioned Macrot. under Act. r., from which it is derived; but as Dr. Scipio's proving (with the 3rd trit., from 9 to 24 grains being taken daily) brought out some features not noted in the Act. r. proving, I think it best to give it an independent mention. Muscular weakness, excessive restlessness, > by moving about in spite of the weakness; melancholy, and irritable; dulness of intellect─these were prominent general features. But the most important distinctive feature is > of symptoms (other than dysmenorrhœa, pains) by onset of menses. C. A. Howell (Med. Adv., xxi. 231) cured with Macr. 2x, every two hours, a woman, 63, who, after an interval of eleven years, began again to menstruate at 60, slightly but regularly, and who had the following symptoms, which appeared suddenly at the time the flow was due, but failed to come …
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