Natrium nitrosum

Sodium nitrite · Human-made/chemical

Clarke

Natrium Nitrosum suits states of acute circulatory collapse with cyanosis, faintness, and copious diarrhoea resembling apoplectic crises. The concomitance of fainting with other symptoms is a guiding keynote. The remedy is closely related to Amyl nitrite and Glonoinum in its vasodilatory pathogenesis.

Key symptoms

  • Intense cyanosis with alarming faintness and tendency to collapse
  • Copious liquid stools at night with faintness as a keynote concomitant
  • Diarrhoea and fainting; bitter eructations and heavily coated tongue
  • Eruption like syphilitic roseola on chest; spreading measly eruption over body
  • Albumin in urine; copious urates
  • Symptoms worse from motion and relieved by lying down

Worse (aggravation)

  • Motion

Better (amelioration)

  • Lying down
John Henry Clarke
A Dictionary of Practical Materia Medica · 1900

Nitrite of Sodium. NaNO2. Trituration. Solution.

Clinical

Angina pectoris. Apoplexy. Cyanosis. Fainting. Gastro-enteritis.

Characteristics

Ringer and Murrell (Lancet, November 3, 1883─C. D. P.) administered ten grains of Na. ntrs., dissolved in an ounce of water, to fourteen men and four women. To twelve men and four women it was given in five-gr. doses. In almost all it produced alarming symptoms of the apoplectic order. A cat had 4 c.c. of a 10 per cent. aqueous solution injected under the skin, and died of the effects. Collischorm (quoted H. P., x. 469) relates two cases of accidental poisoning with Nat. nitros. (1) The first patient was affected with: Diarrhœa and fainting, bitter eructations, heavily coated tongue, and on the chest an eruption like syphilitic roseola. Traces of albumen in urine. During the night, copious alvine discharges with faintishness. The following day, intense cyanosis. Urine dark yellow, containing copious urates. Next day he took 2.5 grin.; cyanosis diminished and the …

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