Nectrianinum

Fungus

Clarke

Nectrianinum is a cancer nosode suited to patients with carcinoma or epithelioma where there are haemorrhages, fetid discharges, and progressive neoplastic growth. In cancerous patients it produces a characteristic febrile reaction not seen in healthy subjects, suggesting its use as a diagnostic and therapeutic agent in malignancy.

Key symptoms

  • Carcinoma and epithelioma with arrest or diminution of haemorrhages
  • Suppression of fetid discharges from cancerous lesions
  • Tendency to epidermisation of neoplasm with arrest of its evolution
  • Febrile reaction with chills, accelerated pulse, palpitation, and headache in cancer patients only
  • Therapeutic crisis terminating in polyuria and profound sleep
  • Worsening when treatment discontinued; improvement when resumed

Worse (aggravation)

  • Discontinuation of treatment

Better (amelioration)

  • Resumption of treatment
John Henry Clarke
A Dictionary of Practical Materia Medica · 1900

Nosode of cancer of trees (Nectria ditissima). Dilution. Trituration of the parasite.

Clinical

Carcinoma. Epithelioma.

Characteristics

Nectrianinum is a clear liquid of a yellowish-brown hue which was prepared by Bra and Chaussé (Med. Rev. of Rev., April, 1900, quoted H. M., xxxv. 533) as follows: Cultures (of Nectria) of two months of age, on grape broth, are evaporated on a water bath until reduced to one-third of their original volume. They are filtered through paper and again through porcelain. The liquid is then taken to the autoclave at a temperature of 120° C. This assures that all spores are killed. Injected into healthy animals in 5 c.c. doses several times a week no result is observed. In cancerous men and animals, on the contrary, the injections cause a rise of temperature in from two to four hours of 1° to 3°. If the dose is increased the hyperthermia is accompanied by chills, sensation of cold, accelerated pulse, palpitation, headache, thirst. The crisis terminates after some hours in polyuria …

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