Picricum acidum
Picric acid (2,4,6-trinitrophenol) · Picric acid, trinitrophenol. · Human-made/chemical
Picric ac. is best suited to people who are prone to intellectual collapse and nervous exhaustion—perhaps students who have studied too hard for exams. They have a tendency to be indifferent, listless, and lack motivation, and the slightest exertion makes them want to lie down. Exhaustion and poor concentration are other common symptoms.
The classic symptom picture for Picric ac. is of indifference with great mental and physical fatigue, which may develop into actual paralysis. Muscular pains in the limbs may accompany fatigue, and there may be weak, heavy sensations in the limbs and back, and burning along the spine, particularly upon any exertion. The hands and feet may feel cold.
Key symptoms
- Causes degeneration of the spinal cord, with paralysis.
- Brainfag and sexual excitement.
- Acts upon the generative organs probably through the lumbar centers of the spinal cord; prostration,...
- Lack of will-power; disinclined to work.
- Head pains; relieved by bandaging tightly.
- Occipital pain; worse, slightest mental exertion.
- Chronic catarrhal conjunctivitis with copious, thick yellow discharge.
- Scanty; complete anuria.
Worse (aggravation)
Better (amelioration)

Picric Acid-Trinitrophenol
Causes degeneration of the spinal cord, with paralysis. Brainfag and sexual excitement. Acts upon the generative organs probably through the lumbar centers of the spinal cord; prostration, weakness and pain of back, pins and needle sensation in extremities. Neurasthenia (Oxal ac). Muscular debility. Heavy tired feeling. Myelitis with spasms and prostration. Writer's palsy. Progressive, pernicious anæmia. Uræmia with complete anuria. A one per cent solution applied on lint, is the best application for burns until granulations begin to form. Sallow complexion.
Mind
Lack of will-power; disinclined to work. Cerebral softening. Dementia with prostration, sits still and listless.
Head
Head pains; relieved by bandaging tightly. Occipital pain; worse, slightest mental exertion. Vertigo and noises in ear. Boils within ears and back of neck. After prolonged mental strain, with anxiety and dread of failure at examination. Brain fag.
Eyes
Chronic catarrhal conjunctivitis with copious, thick yellow discharge.
Stomach
Bitter taste. Aversion to food.
Urinary
Scanty; complete anuria. Dribbling micturition. Urine contains much indican, granular cylinders and fatty degenerated epithelium. Inflammation of kidneys with profound weakness, dark, bloody, scanty urine. Nightly urging.
Male
Emissions profuse, followed by great exhaustion, without sensual dreams. Priapism; satyriasis. Hard erections, with pain in testicles and up cord. Prostatic hypertrophy, especially in cases not too far advanced.
Female
Pain in left ovary and leucorrhœa before menstruation. Pruritus vulvæ.
Extremities
Burning along spine. Great weakness. Tired, heavy feeling all over body, especially limbs; worse, exertion. Feet cold. Cannot get warm. Acute descending paralysis.
Modalities
Worse, least exertion, especially mental, after sleep, wet weather. A summer or hot weather remedy; patient is worse then. Better, from cold air, cold water, tight pressure.
Relationship
Compare: Oxal ac; Gels; Phos; Sil; Arg nit. Compare: Zinc pic (facial palsy and paralysis agitans); Ferr pic (buzzing in ears, deafness; chronic gout; epistaxis; prostatic troubles); Calc pic (boils in and around ears).
Dose
Sixth potency.

Mind
The weakness of body and mind is the first impression wrought upon the mind of the reader who goes carefully over this proving.
It is progressive, passing from weariness to paralysis. The evidences of softening of brain and cord are strong. He, soon becomes sensitive to heat and desires the cool air which ameliorates his head and bodily condition.
Cold air and cold bathing are grateful to him. He is sensitive to wet weather. Numbness of many parts, trembling, lassitude, heaviness, must lie down, worse from least exertion are marked features. Loss of sleep, mental, worry, mental labor, are the exciting causes of symptoms. Extreme indifference.

Picric Acid. Carbazotic Acid. Tri-nitro-carbolic Acid. (C6H2(NO2)3OH). Trituration. Solution in rectified spirit.
Clinical
Acne. Anæmia. Boils. Brain, base of, pain in. Brain-fag. Burns. Cancerous cachexia. Condylomata. Debility. Diabetes. Ears, boils in. Emissions. Enuresis. Epistaxis. Erotomania. Erythema. Hæmoglobinuria. Hands, perspiration of. Headache, of students. Hemiplegia. Jaundice. Leucocythæmia. Liver, congestion of; fatty. Locomotor ataxia. Lumbago. Myelitis. Neurasthenia. Otitis. Paralysis. Paraplegia. Pernicious anæmia. Priapism. Pruritus vulvæ. Self-abuse. Spinal exhaustion. Spinal irritation. Spinal sclerosis. Styes. Sycosis. Urine, bloody. Writer's cramp.

HC6H2(NO2)3O.
Is often restorative of a wasted and worn-out system; a fair picture of "nervous prostration" (Kali p.). Progressive, pernicious, anaemia; neurasthenia. Brain fag: of literary or business people; slightest excitement, mental exertion or overwork brings on headache, and causes burning along the spine (Kali p.). Headache: of students, teachers and overworked business men; from grief or depressing emotions; in occiputal-cervical region (Nat. m., Sil.); < or brought on by slightest motion or mental exertion. Priapism, with spinal disease; erections; satyriasis (Canth., Phos.). Small boils in any part of body, but especially in external auditary canal. Burning along spine and great weakness of spine and back; softening of cord (Phos., Zinc.). Weariness, progressing from a slight feeling of fatigue on motion to complete paralysis. Tired heavy feeling all over body, especially of limbs, < on exertion.

Mind
Great indifference and lack of will power to do anything.
Male Sexual Organs
Priapism associated with spinal disease; terrible erections.
Generalities
Great mental and physical prostration < by reaching, reading, writing, or thinking.

- Brain fag and neurasthenia, especially sexual; great mental and physical prostration from reading, writing, or any attempt at mental labour.

Phatak's chapter on Picricum acidum is available in the app.
Read Phatak in the appClassical texts are in the public domain. Educational reference only — not medical advice.