Pilocarpinum

Pilocarpine (alkaloid from Pilocarpus) · Plant · Rutaceae

Clarke

Pilocarpinum suits individuals with excessive secretions, particularly profuse sweating and salivation, combined with ear disorders such as labyrinthine deafness and tinnitus. It is most effective in patients who are more deaf when tired or have a syphilitic background.

Key symptoms

  • Profuse sweating with salivation
  • Labyrinthine deafness with tinnitus and auditory nerve vertigo
  • Contraction of pupils when applied locally to the eye
  • Excessive salivation during pregnancy
  • Alopecia
  • Uremic or puerperal convulsions
  • Albuminuria

Worse (aggravation)

  • After cold (hearing worsens)
  • Fatigue (deafness increases)

Better (amelioration)

  • In a noise such as a train (hearing improved)
John Henry Clarke
A Dictionary of Practical Materia Medica · 1900

PILOCARPINUM. Pilocarpia. Pilocarpine. C11H16N2O2. Solution in distilled water.

Clinical

Albuminuria. Alopecia. Convulsions, uræmic; puerperal. Deafness. Ménière's disease. Mumps. Myopia. Perspiration, excessive. Pregnancy, nausea of; salivation of. Salivation. Vertigo, aural.

Characteristics

Pilocarpin. is one of the most characteristic of several alkaloids which have been isolated from Jaborandi (Pilocarpus pinnatus). It has been used, like Jabor., to produce and cure profuse sweating; and by oculists to produce contraction of the pupil, which it does whether it is injected subcutaneously or applied directly to the eye. It has also an action on the ear. G. P. Field (Brit. Med. Jour., May 17, 1890, &c.) has given it with good effect in labyrinthine deafness, tinnitus, and auditory nerve vertigo. The cases least amenable to its influence were those in which the hearing was > in a noise as of a train, &c.; and those in which the hearing is < after a cold. Subjects of syphilis, hereditary or acquired, …

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Classical texts are in the public domain. Educational reference only — not medical advice.

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