Saccharinum

Saccharin; benzoic sulphinide; o-sulphobenzoic acid imide; 1,1-dioxo-1,2-benzothiazol-3(2H)-one (IUPAC). The commercial sweetener is usually the sodium salt (sodium saccharin). · Saccharin, artificial sweetener, "coal-tar sugar," benzosulphimide, Sweet'N Low (sodium salt). Not to be confused with Saccharum officinale (cane sugar), Saccharum lactis (milk sugar), or Saccharum album (white sugar) — all distinct remedies.

Modern MM

Sphere of action is essentially digestive/secretory, inferred from saccharin's known interference with salivary and peptic ferments — dyspepsia, anorexia, diarrhoea and wasting. The only formally listed mental indication is "indifference" (HPUS). There is no substantial proving-derived symptom picture; published homeopathic sources explicitly note the absence of a materia medica for this remedy.

Key symptoms

Indifference (sole HPUS-listed indication). Digestive sphere, inferred from toxicology: impaired salivary and gastric (peptic) digestion with dyspepsia; loss of appetite; pain in the right hypogastrium; diarrhoea; emaciation/wasting from inhibited secretory-cell function. These are toxicological/pharmacological indications under the Law of Similars, NOT verified proving keynotes.

Worse (aggravation)

Not established. No proving-derived modalities exist for Saccharinum.

Better (amelioration)

Not established. No proving-derived modalities exist for Saccharinum.

Manohar V Nagaiah

Materia Medica of Modern Homeopathic Medicine · 2026

Saccharin, artificial sweetener, "coal-tar sugar," benzosulphimide, Sweet'N Low (sodium salt). Not to be confused with Saccharum officinale (cane sugar), Saccharum lactis (milk sugar), or Saccharum album (white sugar) — all distinct remedies.

Source & Nature

Saccharinum is the potentised preparation of saccharin, the first synthetic non-nutritive sweetener and a coal-tar (benzene) derivative. The acid form is C7H5NO3S (mol. wt. 183.18; CAS 81-07-2; PubChem CID 5143; IUPAC 1,1-dioxo-1,2-benzothiazol-3(2H)-one, also called benzoic sulphinide). The water-soluble commercial sweetener is the sodium salt, sodium saccharin (C7H4NNaO3S; PubChem CID 656582).

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Classical texts are in the public domain. Educational reference only — not medical advice.