Sulphanilamidum

Sulfanilamidum; 4-aminobenzene-1-sulfonamide (IUPAC); p-aminobenzenesulfonamide; para-aminobenzolsulfonamid (PABS) · Sulfanilamide; Sulfa; Streptocide (Strepticid); Prontylin; Ambeside; Lysococcin; PABS. (Note: Prontosil is the related azo prodrug metabolized to sulfanilamide, not sulfanilamide itself.)

Modern MM

A "modern" drug remedy chiefly answering to states reflecting its pharmaco-toxic action: low-vitality/septic febrile states with prostration; drug-toxicity pictures with lassitude and CNS depression; and renal/urinary irritation from crystalluria. Indications are predominantly toxicologically derived (Law of Similars), supported by a single 1943 proving whose detailed symptom text is not openly available.

Key symptoms

Indications are chiefly inferred from sulfanilamide's known toxicology (Law of Similars), with a 1943 Hahnemannian proving by Sutherland on record (detailed symptoms not openly available): low, adynamic febrile states with marked prostration and lassitude; dusky blueness/cyanosis of the skin (methemoglobinemia, historically reported with sulfanilamide); constitutional drug-toxicity malaise — drug fever, anorexia, nausea; CNS depression/confusion with drowsiness and vertigo; and urinary irritation with crystalluria, hematuria and scanty/suppressed urine. NOTE: specific characteristic mind/particular "keynotes" from the proving are not reproduced in openly available sources and are NOT asserted here.

Worse (aggravation)

Not established from a published proving in the open literature. No reliable, sourced modalities can be stated.

Better (amelioration)

Not established from a published proving in the open literature. No reliable, sourced modalities can be stated.

Manohar V Nagaiah

Materia Medica of Modern Homeopathic Medicine · 2026

Sulfanilamide; Sulfa; Streptocide (Strepticid); Prontylin; Ambeside; Lysococcin; PABS. (Note: Prontosil is the related azo prodrug metabolized to sulfanilamide, not sulfanilamide itself.)

Source & Nature

Sulphanilamidum is the homeopathic preparation of sulfanilamide (4-aminobenzene-1-sulfonamide; C6H8N2O2S, MW 172.20, CAS 63-74-1, PubChem CID 5333), the prototype sulfonamide antibacterial drug. Chemically it is an aniline ring carrying a sulfonamide group — an aromatic (organic) carbon compound. First synthesized by Paul Gelmo in 1908, its antibacterial action was discovered in the 1930s when Domagk's dye Prontosil was found to be metabolized to sulfanilamide; it acts as a PABA analogue that inhibits bacterial dihydropteroate synthase, blocking folate synthesis. It is the historic substance of the 1937 Elixir Sulfanilamide disaster, in which the diethylene-glycol solvent (not the drug) caused over 100 deaths and led to the U.S. 1938 Food, Drug & Cosmetic Act.

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Classical texts are in the public domain. Educational reference only — not medical advice.