Ampicillinum

Ampicillin; (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; alpha-aminobenzylpenicillin · Ampicillin, aminobenzylpenicillin, "amp"; trade names historically Penbritin, Polycillin, Principen, Omnipen

Modern MM

A modern drug remedy whose sphere of action is inferred from ampicillin's toxicology: skin (allergic eruptions), the gastrointestinal mucosa and bowel flora (diarrhea, colitis), and the mucous membranes. There is NO proving-derived mental/constitutional picture. Conceptually used, where used at all, as a same-substance remedy for the adverse effects of ampicillin/penicillin-class antibiotics.

Key symptoms

These are TOXICOLOGICAL indications (Law of Similars), not proving keynotes: ill-effects of ampicillin / penicillin-class antibiotics; itching maculopapular drug rash and urticaria; antibiotic-associated diarrhea and pseudomembranous (C. difficile) colitis; "black hairy tongue" following antibiotic use; nausea and vomiting; history of penicillin hypersensitivity (up to anaphylaxis). No verified mental or constitutional keynotes exist.

Worse (aggravation)

Not established. No proving-derived modalities exist for this remedy. Any aggravation pattern would have to come from the individual case, not from the literature.

Better (amelioration)

Not established. No proving-derived modalities exist for this remedy.

Manohar V Nagaiah

Materia Medica of Modern Homeopathic Medicine · 2026

Ampicillin, aminobenzylpenicillin, "amp"; trade names historically Penbritin, Polycillin, Principen, Omnipen

Source & Nature

Ampicillinum is the potentised form of ampicillin, a semi-synthetic aminopenicillin beta-lactam antibiotic (molecular formula C16H19N3O4S, molecular weight 349.4, CAS 69-53-4, PubChem CID 6249 — all confirmed against the PubChem record). Discovered in 1958 and in commercial use from 1961 via Beecham, it was the first broad-spectrum penicillin, active against both gram-positive and gram-negative bacteria. It belongs to the class of modern medicinal-drug remedies rather than to a botanical, mineral or animal source.

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Classical texts are in the public domain. Educational reference only — not medical advice.