Aspartamum

N-L-α-Aspartyl-L-phenylalanine 1-methyl ester (L-aspartyl-L-phenylalanyl methyl ester). PubChem (CID 134601) lists the canonical IUPAC name of the parent acid as "(3S)-3-amino-4-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid"; aspartame is the corresponding methyl ester. · Aspartame; NutraSweet; Equal; Canderel; E951

Modern MM

A modern remedy made from the artificial sweetener aspartame. A formal Hahnemannian proving (placebo-controlled) is catalogued — Richard Bocock / South Downs School of Homoeopathy, 2002, remedy by Helios (verified on provings.info) — but the detailed symptom record is held behind restricted/logged-in access; published, freely verifiable symptom detail is therefore limited. Any organ-affinity statements below the proving level rest on aspartame's known metabolic/toxicological action (phenylalanine, aspartate, methanol).

Key symptoms

A Hahnemannian proving of Aspartamum (placebo-controlled) was conducted by Richard Bocock and the South Downs School of Homoeopathy (2002, remedy by Helios), establishing the remedy as a proven medicine — this existence and provenance are confirmed via provings.info. However, the detailed proving symptom list — specific mind, generality and particular keynotes — is held behind restricted archive access and is not freely verifiable; this curation therefore does NOT list specific keynotes, which should be read directly from the original proving document rather than inferred or invented. The only publicly traceable reference points are toxicological: neurological complaints anecdotally reported by sensitive individuals (headache, dizziness, mood change), and the absolute contraindication signal of phenylalanine accumulation in phenylketonuria.

Worse (aggravation)

Not reliably established in publicly available sources. The full Bocock (2002) proving record — which would contain proving modalities — is held behind restricted/logged-in homeopathic archive access and could not be verified here; no aggravations are asserted, to avoid fabrication.

Better (amelioration)

Not reliably established in publicly available sources (see Aggravation). Not asserted.

Manohar V Nagaiah

Materia Medica of Modern Homeopathic Medicine · 2026

Aspartame; NutraSweet; Equal; Canderel; E951

Source & Nature

Aspartamum is the homeopathic remedy prepared from aspartame, a synthetic high-intensity sweetener (methyl ester of the L-aspartyl-L-phenylalanine dipeptide). Molecular formula C14H18N2O5, MW 294.30 g/mol, CAS 22839-47-0, PubChem CID 134601 (all confirmed against PubChem). It is about 200 times sweeter than sucrose and is marketed as NutraSweet, Equal and Canderel and as food additive E951. Discovered accidentally by James Schlatter at G.D. Searle in 1965, it is now present in roughly 6,000 consumer products.

Preparation

Made from pharmaceutical-grade aspartame by trituration with lactose through the centesimal stages, then liquid potentisation in ethanol–water per the Homoeopathic Pharmacopoeia (Remedia lists it under "Regulation 5a, C3"). Supplied as medicated saccharose globules and liquid dilutions by Remedia, Helios and other homeopathic pharmacies.

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Classical texts are in the public domain. Educational reference only — not medical advice.