Glonoinum
Glyceryl trinitrate (nitroglycerin) · Nitroglycerine, trinitroglycerine, glyceryl trinitrate,Trinitrum · Human-made/chemical
Symptoms that are treated with Glonoinum focus on the regulation of the circulation between the head and the heart. The remedy is used when an increase in blood supply causes hot flashes, similar to those experienced during heatstroke, which surge up to the brain in waves, resulting in severe headaches. There is typically a bursting, “full” sensation in the head, with great confusion and a compulsion to hold the head and squeeze it. Glonoinum is also used for high blood pressure, particularly in the elderly, for heat exhaustion, and for menopausal hot flashes.
Key symptoms
- Congestive headaches with surging of blood to head and heart
- Head feels enormously large; skull too small for brain
- Sun headache; increases and decreases with the sun
- Cannot bear any heat about the head; better from uncovering head
- Throbbing, pulsating pains throughout the body synchronous with pulse
- Violent convulsions associated with cerebral congestion
- Threatened apoplexy; cannot recognize familiar localities
- Headache in place of menses; rush of blood to head in pregnant women
Worse (aggravation)
Better (amelioration)

Nitro-glycerine--Spirits Glycerinus Nitrate
Recent German provings of Glonoine confirm the original American provings and clinical indications and bring out very marked nerve disturbances. Great lassitude, no inclination to work; extreme irritability, easily excited by the slightest opposition, ending in congestive head symptoms. The sixth potency alone produced itching all over body with later acne and furuncle formation, also bulimy.
Great remedy for congestive headaches, hyperæmia of the brain from excess of heat or cold. Excellent for the intercranial, climacteric disturbances, or due to menstrual suppression. Children get sick when sitting before an open fire. Surging of blood to head and heart. Tendency to sudden and violent irregularities of the circulation. Violent convulsions, associated with cerebral congestion. Sensation of pulsation throughout body. Pulsating pains. Cannot recognize localities. Sciatica in other-omatous subjects, with cold shriveled limbs; seasickness.
Head
Confusion, with dizziness. Effects of sunstroke; heat on head, as in type-setters and workers under gas and electric light. Head heavy, but cannot lay it on pillow. Cannot bear any heat about head. Better from uncovering head. Throbbing headache. Angio-spastic neuralgia of head and face. Very irritable. Vertigo on assuming upright position. Cerebral congestion. Head feels enormously large, as if skull were too small for brain. Sun headaches; increases and decreases with the sun. Shocks in head, synchronous with pulse. Headache in place of menses. Rush of blood to head in pregnant women. Threatened apoplexy. Meningitis.
Eyes
See everything half light, half dark. Letters appear smaller. Sparks before eyes.
Mouth
Pulsating toothache.
Ears
Throbbing; each beat of heart is heard in ears; full feeling.
Face
Flushed, hot, livid, pale; sweaty; pains in root of nose; faceache. Dusky face.
Throat
Neck feels full. Collars must be opened. Chokes and swells up under ears.
Stomach
Gastralgia in anæmic patients with feeble circulation. Nausea and vomiting. Faint, gnawing, and empty feeling at pit of stomach. Abnormal hunger.
Abdomen
Constipation with itching, painful hæmorrhoids, with pinching in abdomen before and after stool. Diarrhœa; copious blackish, lumpy stools.
Female
Menses delayed, or sudden cessation with congestion to head. Climacteric flushing.
Heart
Laborious action. Fluttering. Palpitation with dyspnœa. Cannot go uphill. Any exertion brings on rush of blood to heart and fainting spells. Throbbing in the whole body to finger-tips.
Extremities
Itching all over, worse extremities. Pain in left biceps. Drawing pain in all limbs. Backache.
Modalities
Better, brandy. Worse, in sun; exposure to sun-rays, gas, open fire; jar, stooping, having hair cut; peaches, stimulants; lying down; from 6 am to noon; left side.
Relationship
Antidote: Acon.
Compare: Amyl nit; Bellad; Opium; Stram; Verat vir.
Dose
Sixth to thirtieth potency.
For palliative (non-homeopathic) purposes, in angina pectoris, asthma, heart-failure, etc, physiological doses-i.e, 1-100 of drop-must be given. Here it is the great emergency remedy. The conditions calling for it are small, wiry pulse, pallor, arterial spasm, anæmia of brain, collapse, feeble heart, syncope, dicrotic pulse, vertigo,-the opposite of those indicating a homeopathic dosage. Often thus used to lower the arterial tension in chronic interstitial nephritis.

Head
The most common feature in this remedy is the surging of blood to the head and to the heart. A patient often describes the state as a feeling as if all the blood in the body must be rushing around the heart, with a sense of heat or a boiling sensation in the region of the heart, or in the left side of the chest.
Again he complains of a surging in the head, a warm glowing sensation in the head or a feeling of intense glowing from the stomach or from the chest up into the head, attended at times with loss of consciousness.
There are also wave-like sensations in the head, as if the skull were being lifted up and lowered, or as if it were being expanded and contracted. Along with this there is most intense pain, sometimes as if the head would burst, sometimes great soreness in the head, or a sense of soreness felt in the skull. Another accompaniment of the surging is great throbbing, synchronous with the heat of the heart, and when the skull has this soreness then the throbbing is like the beating of hammers, and every pulsation is painful, so that there are painful pulsations and sometimes painless pulsations.

Nitro-glycerine. C3 H5 (NO3) O3. Dilutions with alcohol.
Clinical
Angina pectoris. Aphasia. Apoplexy. Brain, congestion of. Bright's disease. Convulsions. Epilepsy. Epistaxis. Fright, effects of. Goître. Headache. Heart, affections of; palpitation of; jarring, effects of. Location, sense of, lost. Mania. Meningitis. Menses, suppression of. Neuralgia. Paralysis. Rheumatism. Sciatica. Sea-sickness. Snow-headache. Sun-headache. Sunstroke. Toothache. Trauma.
Characteristics
"Nitro-glycerine was discovered by Sobrero in 1847, but none could be obtained for physiological experiment until Morris Davis, a Philadelphia chemist, in the same year, after long and laborious trials, under direction of Hering, succeeded in producing the substance in sufficient quantities for proving." I quote this from the Guiding Symptoms. Glon. is one of the many monuments of Hering's therapeutic genius. It is to him that we owe the introduction of this notable remedy into the materia medica, and into medicine. The note of the …

Nitro-glycerine. (C3H4(NO2)O3)
Nervous temperament; plethoric, florid, sensitive women; persons readily affected. Bad effects of mental excitement, fright, fear, mechanical injuries and their later consequences; from having the hair cut. (Acon., Bell.). Head troubles: from working under gas-light, when heat falls on head; cannot bear heat about the head, heat of stove or walking in the sun (Lach., Nat. c.). Cerebral congestion, or alternate congestion of the head and heart. Head: feels enormously large; as if skull were too small for brain; sunstroke and sun headache; increases and decreases every day with the sun (Kal., Nat. c.). Terrific shock in the head, synchronous with the pulse. Throbbing, pulsating headache; holds head with both hands; could not lie down, "the pillow would beat.". Brain feels too large, full, bursting; blood seems to be pumped upwards; throbs at every jar, step, pulse. Intense congestion of brain from delayed or suppressed menses; headache in place of menses. Headache: occurring …

Mind
Confusion, cannot tell where he is; well known streets seem strange; forgets on which side of the street he lives.
Head
Headache from recent exposure to the sun.
Head
Headache from below upwards; brain as if moving in waves.
Head
Fullness of the head, distinct feeling of a pulse in the head; throbbing with or without pain.
Head
Is afraid to shake the head, it increases the ache and seems as though the head would drop in pieces.
Sight and Eyes
Eyes injected, protruding, look wild, pupils dilated, objects dance before them with every pulsation.
Heart and Pulse
Violent action of the heart, distinct pulsation over the whole body, especially in back of neck and head.

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Confusion of ideas, cannot tell where he is, streets seem strange, and the way home too long.
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Sensation as if the head was enormously large.
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Distinct feeling of the pulse in the head, throbbing without pain.
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Undulating or wave-like motion in the brain.
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Violent action of the heart, distinct pulsation over the whole body.
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Bad effects from exposure to the rays of the sun.

Phatak's chapter on Glonoinum is available in the app.
Read Phatak in the appClassical texts are in the public domain. Educational reference only — not medical advice.