Procainum

2-(Diethylamino)ethyl 4-aminobenzoate (IUPAC). Procaine hydrochloride is the common salt form. · Procaine, Novocaine / Novocain, procaine HCl, allocaine; historic trade name Novocain. (Distinct from procainamide, an antiarrhythmic amide derivative.)

Modern MM

A sphere of action centred on the nervous system and conduction tissue, derived from procaine's known sodium-channel-blocking and local-anaesthetic toxicology: numbness and paraesthesia, neural over-excitation progressing to depression, and cardiac conduction disturbance. There is no formal proving; this is a toxicologically-derived profile only.

Key symptoms

No formal homeopathic proving exists, so there are no validated keynotes or mentals. The toxicologically-documented signature (not classical keynotes) is: circumoral/perioral numbness and tingling with a metallic taste; tinnitus, dizziness, blurred vision; restlessness, anxiety and agitation passing into tremor, muscle twitching and convulsions, then drowsiness, collapse and respiratory failure; cardiac conduction block and arrhythmia. Allergic/anaphylactoid reactions reflect the PABA metabolite. These are presented as the substance's toxicological picture only, not as proven remedy keynotes.

Worse (aggravation)

Not established. No proving-derived or toxicologically-defined modalities of aggravation are documented for Procainum; none are asserted.

Better (amelioration)

Not established. No proving-derived or toxicologically-defined modalities of amelioration are documented for Procainum; none are asserted.

Manohar V Nagaiah

Materia Medica of Modern Homeopathic Medicine · 2026

Procaine, Novocaine / Novocain, procaine HCl, allocaine; historic trade name Novocain. (Distinct from procainamide, an antiarrhythmic amide derivative.)

Source & Nature

PROCAINUM is the homeopathic name for procaine, a synthetic aminoester local anaesthetic of the para-aminobenzoic acid (PABA) series. The free base is C13H20N2O2 (CAS 59-46-1, PubChem CID 4914); the usual pharmaceutical salt is procaine hydrochloride, C13H21ClN2O2 (CAS 51-05-8, PubChem CID 5795). It was first synthesised in 1905 by the German chemist Alfred Einhorn as a safer alternative to cocaine and introduced into surgery by Heinrich Braun under the trade name Novocain.

Commercially it has been used as an injectable local and regional anaesthetic in dentistry, infiltration and neuraxial blocks, and as a depot carrier for intramuscular penicillin (penicillin G procaine). It should be distinguished from procainamide, a related amide antiarrhythmic.

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Classical texts are in the public domain. Educational reference only — not medical advice.