Progesteronum

Progesterone; pregn-4-ene-3,20-dione (IUPAC); C21H30O2; CAS 57-83-0; PubChem CID 5994; MW 314.5 g/mol · Progesteron; Gelbkörperhormon (corpus luteum hormone); Gestagen; Corpus luteum hormone

Modern MM
Hormonal/organotherapeutic remedy of the female reproductive sphere. Used as an isopathic/organotherapy preparation for luteal-phase and progesterone-related complaints — menstrual cycle regulation, premenstrual and menopausal symptoms — rather than from a classical proving picture.

Key symptoms

No keynotes from a formal proving exist. Clinical/organotherapeutic indications (from homeopathic pharmacy and prescribing usage, inferred from the hormone's action under the Law of Similars): disorders of the menstrual cycle and luteal-phase (corpus luteum) insufficiency; premenstrual syndrome with breast tenderness, irritability and fluid retention; menopausal complaints (hot flushes, mood disturbance); used to support cycle regulation and as an adjunct in fertility/ovulation support. These are functional/clinical indications, NOT proving symptoms.

Worse (aggravation)

Not established. No proving-derived modalities exist for this remedy; aggravation patterns cited in classical materia medica are absent.

Better (amelioration)

Not established. No proving-derived amelioration modalities exist for this remedy.
Manohar V Nagaiah
Materia Medica of Modern Homeopathic Medicine · 2026

Progesteron; Gelbkörperhormon (corpus luteum hormone); Gestagen; Corpus luteum hormone

Source & Nature

Progesteronum is the homeopathic preparation of progesterone, the endogenous progestogen steroid hormone (pregn-4-ene-3,20-dione; C21H30O2; MW 314.5; CAS 57-83-0; PubChem CID 5994). A cholesterol-derived C21 steroid, it is secreted mainly by the ovarian corpus luteum, the adrenal cortex, and the placenta during pregnancy. It also exists as the prescription drug 'micronized progesterone' (e.g. Prometrium).

In homeopathy it is also listed under Progesteron, Gelbkörperhormon (corpus luteum hormone) and Gestagen.

Preparation

Made by homeopathic potentization of progesterone. As the steroid is poorly water-soluble, low stages are prepared by trituration with lactose and/or solution in ethanol-water, followed by serial dilution and succussion. It is commercially available across the decimal (D/X), centesimal (C/CH), Korsakovian (K/MK) and LM/Q scales (Remedia: D12-D200, C6-C200, 1MK-100MK, LM1-LM30; Boiron: 4CH-30CH, 200K and higher Korsakovian).

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Classical texts are in the public domain. Educational reference only — not medical advice.

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