Salol

Phenyl salicylate · Human-made/chemical

Clarke

Salol suits patients with rheumatic joint pains, soreness, and stiffness, particularly affecting buttocks, knees, and wrists. The remedy is also indicated in acute diarrhoea, dysentery, and conditions requiring intestinal antisepsis. It acts when salicylate-type symptoms dominate with pronounced violent headache.

Key symptoms

  • Very violent headache, more severe than any previously experienced by the prover
  • Rheumatic pains in joints with soreness and stiffness
  • Pain and soreness especially in buttocks, knees, and wrists
John Henry Clarke
A Dictionary of Practical Materia Medica · 1900

Salicylate of Phenol. C6H4 OH ─ C6H4 COOC6H5. Trituration.

Clinical

Diarrhœa. Dysentery. Fever. Gonorrhœa. Headache. Influenza. Neuralgia. Rheumatism. Small-pox.

Characteristics

Salol was primarily used as an anti-rheumatic, especially in the treatment of acute cases. It was given as an antipyretic, in 30 to 45 grain doses, in powders or tablets. It is soluble in ether and petroleum spirit; very sparingly, if at all, in water. It does not disturb digestion because it passes through the stomach unaltered, being decomposed in the duodenum, by the ferments of the pancreas, into Salicylic acid and Phenol (it contains 38 per cent. of Phenol). These are excreted by the kidneys, and the condition of intestinal digestion has been estimated by the length of time required, after the ingestion of Salol, for them to appear in the urine. Upon this property also has been based the use of the remedy in acute diarrhœa, dysentery, cholera, and other diseases where intestinal asepsis is indicated, and also in affections …

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Classical texts are in the public domain. Educational reference only — not medical advice.

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