Spigelia marilandica
Plant · Loganiaceae
A remedy producing acute mental derangement resembling Stramonium with running, skipping movements and inappropriate laughing and crying. The symptoms include eye muscle dysfunction with strabismus and marked pupil dilation.
Key symptoms
- Mania with wild and incoherent talk
- Complete mental derangement
- Strabismus of right eye
- Pupils greatly dilated
- Wild staring expression
- Trembling and exhaustion
- Skin hot and dry

Spigelia Marilandica. Pink-root. Worm-grass. N. O. Loganiaceæ. Tincture of root.
Clinical
Mania. Strabismus (r.).
Characteristics
The symptoms of Spi. m. are mainly from overdosing. A state of mania was induced in a boy from large and frequent doses of a decoction of the root. Strabismus of right eye was noted in one case.
1. Mind
Suddenly affected with complete mental derangement, exactly like that of Stram., countenance distorted, running and skipping, fits of laughing and crying, pupils greatly dilated, talk wild and incoherent, (lasted 24h.).
2. Head
Vertigo.
3. Eyes
Wild, staring, ludicrous expression.─Irregular movement of adductors and abductors of eyes.─Strabismus of r. eye.─Pain in and about the eyes.─Sensation of stiffness of eyelids.─Pupils dilated.
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