Strychninum purum
Strychnine · Plant · Loganiaceae
Suited to persons with extreme reflex excitability of the spinal cord, producing convulsive and tetanic states. The remedy acts most powerfully on the nervous system and skeletal muscles, and is particularly indicated in conditions where the slightest external stimulus — touch, noise, odor — precipitates violent spasms or electric shock-like pains.
Key symptoms
- Tetanic convulsions with opisthotonos; muscles rigid between paroxysms
- Extreme sensitivity to touch, noise, and smell triggering spasms
- Violent jerking, twitching, and shocks throughout muscles
- Stiffness of cervical muscles and entire back
- Bursting headache with heat in eyes and roaring in ears
- Spasm of larynx and pharynx; choking; deglutition impossible
- Acute hearing; every sound intolerable
- Pains and sensations come suddenly and return at intervals
- Icy sensation running down the spine
- Persistent cough recurring after influenza
Worse (aggravation)
- Morning
- Touch
- Noise
- Motion
- After meals
- Exertion and walking
- Slightest draft of air
Better (amelioration)
- Lying on back
- Rest

Alkaloid of Nux Vomica (STRYCHNINUM)
Its primary function is to stimulate the motor centers and the reflex action of the spinal cord. Homeopathic to spasms of muscles, cramps from an undue reflex excitability of the cord, spasms of the bladder, etc. Strychnin stimulates the central nervous system, mental activities, special senses rendered more acute. Respiration increased. All reflexes are made more active. Stiffness in muscles and face and neck. Opisthotonos. Tetanic convulsions with opisthotonos. The muscles relax between paroxysms; worse slightest touch, sound, odor. Influences more directly the spinal cord and is less appropriate in visceral derangements than Nux. Tetanus. Explosive nervousness. The pains and sensations come suddenly and return at intervals.
Head
Restless. Over-irritability. Full and bursting headache, with heat in eyes. Vertigo, with roaring in ears. Jerking of head forwards. Scalp sore. Itching of scalp and nape.
Eyes
Hot, painful, protruding, staring. Pupils dilated. Sparks before eyes. Spasmodic contraction of ocular muscles; twitching and trembling of lids.
Ears
Hearing very acute; burning, itching, and roaring in ears.
Face
Pale, anxious, livid. Jaws stiffened; lower jaw spasmodically closed.
Throat
Dry, contracted; feeling of a lump. Deglutition impossible. Burning along and spasms of œsophagus. Violent itching in roof of mouth.
Stomach
Constant retching. Violent vomiting. Nausea of pregnancy.
Abdomen
Sharp pain in abdominal muscles, griping pain in bowels.
Rectum
Feces discharged involuntarily during spasms. Very obstinate constipation.
Female
Desire for coitus (Canth; Camph; Fl ac; Lach; Phos; Plat). Any touch on body excites a voluptuous sensation.
Respiratory
Spasm of muscles about larynx. Excessive dyspnœa. Sharp, contractive pains in muscles of chest. Persistent cough, recurring after influenza.
Back
Rigitidy of cervical muscles. Sharp pain in nape and down spine. Back stiff; violent jerks in spinal column. Icy sensation down spine.
Extremities
Limbs stiff. Rheumatism with stiff joints. Violent jerking, twitching, and trembling. Tetanic convulsions and opisthotonos; spasms provoked by slightest touch and attempt to move. Shocks in the muscles. Cramp-like pains.
Fever
Cold chills down spine. Perspiration in a stream down head and chest. Lower extremities cold.
Skin
Itching of whole body, especially nose. Icy sensation down the spine.
Modalities
Worse, morning; touch; noise; motion; after meals. Better, lying on back.
Relationship
Compare: Eucalyptus (neutralizes ill effects of Strychnin). Strych ars (Paresis in the aged, relaxed musculature. Prostration. Psoriasis; chronic diarrhœa with paralytic symptoms; compensatory hypertrophy of heart with beginning fatty degeneration; marked dyspnœa when lying down; œdema of lower extremities, urine scanty, high specific gravity, heavily loaded with glucose. Diabetes. 6x trit). Strych et Ferr cit (chlorotic and paralytic conditions; dyspepsia, with vomiting of ingesta; 2x and 3x trit); Strychnin nit (2x and 3x. Said to remove craving for alcohol. Use for two weeks); Strychnin sulph (Gastric atony); Strych valerin (exhaustion of brain-power; women of high nervous erethism; 2x trit). Compare: Cicuta; Arnica (tetanus).
Dose
Third to thirtieth potency. For non-homeopathic use, to produce its direct physiological effects in paralysis the dose will range from one-fiftieth to one-twentieth of a grain, repeated three times a day. Under twelve years of age, one-fiftieth to one two-hundredth of a grain. Strych, hypodermically, is capable of arresting progressive muscular atrophy, and is a certain stimulant to the respiratory centers, and is useful in embarrassed breathing, in the course of pneumonia especially. Is an antidote to Chloral, used in asphyxia from gas and chloroform and early stages of Opium poisoning. Dose, one one-hundredth to one-sixtieth grain every three hours.

STRYCHNINUM. Strychnia. Strychnine. An alkaloid obtained from several species of Strychnos. C21H22N2O2. Trituration. Solution. [The Liquor Strychniæ of B. P. is a solution of the alkaloid in a very weak solution of hydrochloric acid and alcohol, the proportions being: Strychnia gr. iv., diluted hydrochloric acid min. vi., rectified spirit two drachms, distilled water six drachms]
Clinical
Amaurosis. Aorta, pain in. Aphonia. Asthma. Athetosis. Bladder, paralysis of; pains in. Breasts, pains in. Cough, explosive. Cramps Diaphragm, spasms of. Emphysema. Enuresis. Exophthalmos. Eyes, optic nerve, sclerosis of (n). Headache. Hemiplegia. Influenza. Joints, stiffness of. Laryngeal crises of locomotor ataxy. Locomotor ataxy. Malar bones, pains in. Neurasthenia (p). Night-blindness. Paraplegia. Proctalgia. Rheumatism. Scrotum, abscess of. Spinal irritation (p). Tetanus.

Phatak's chapter on Strychninum purum is available in the app.
Read Phatak in the appClassical texts are in the public domain. Educational reference only — not medical advice.