Trimethylaminum
Trimethylamine · Human-made/chemical
Trimethylaminum suits acute rheumatic states with prominent joint pains, particularly in the wrists and ankles, accompanied by great restlessness. The combination of diarrhea with ankle-joint pains and thirst for large quantities of cold water are characteristic guiding symptoms.
Key symptoms
- Great pains in wrist-joints
- Great restlessness with pains in ankle-joints from standing
- Ankle pains worse from slight movement
- Rheumatism so severe the needle held in fingers becomes too heavy to sew
- Copious diarrhea with pains in ankle-joints
- Thirst for large quantities of cold water
Worse (aggravation)
- Slight movement (ankle pains)
- Standing

Propylaminum. N(CH3)3. [Found in many plants, Chen. v., Cratæg. ox., Phal. imp., Pyr. com., Arn., Cotyl. u., Fag. syl., &c., and in herring-brine.] Solution.
Clinical
Ankles, pains in. Rheumatic fever. Wrists, pains in.
Characteristics
Trimethyl., which is prepared from herring-brine among other sources, has a very unpleasant and penetrating fish-like odour. At one time it was regarded as a panacea in cases of acute rheumatism. Experiments on patients and others show that it diminishes the amount of urea excreted. Hansen gives these as characteristics: great pains in wrist-joints, also great restlessness, pains in ankle-joints from standing < slight movement. C. Carleton Smith (H. P., vi. 432) gives these: "Rheumatism, when the needle held in the fingers gets so heavy she cannot sew." "Copious diarrhœa with pains in ankle-joints but not in wrists; thirst for large quantities of cold water (like Bry.)."
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